Have you looked at the Scope Workflow from Esko Graphics
Seeing you are in the point of purchase market, Esko Graphics is the
dominent workflow in that and the packaging market.
http://www.esko-graphics.com/
They would also prove to be a valuable resource as they have a ton of experience in this market.
Here is an interesting link.
http://www.esko-graphics.com/press_releases.asp?id=557
If you have anyquestions about the workflow feel free to ask.
The person to contact at Esko Graphics is..
Andy Redman - Technical Sales / Business Development
Tel. +1(414)339-9196 - Fax +1(262)502-7805